Version 5.4
Bos taurus Protein: FZD10
Summary
InnateDB Protein IDBP-700648.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FZD10
Protein Name frizzled-10
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000009267
InnateDB Gene IDBG-647861 (FZD10)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
GO:0017147 Wnt-protein binding
GO:0030165 PDZ domain binding
GO:0042813 Wnt-activated receptor activity
Biological Process
GO:0001944 vasculature development
GO:0007166 cell surface receptor signaling pathway
GO:0007275 multicellular organismal development
GO:0007420 brain development
GO:0008406 gonad development
GO:0016055 Wnt signaling pathway
GO:0032855 positive regulation of Rac GTPase activity
GO:0032956 regulation of actin cytoskeleton organization
GO:0034259 negative regulation of Rho GTPase activity
GO:0038031 non-canonical Wnt signaling pathway via JNK cascade
GO:0043507 positive regulation of JUN kinase activity
GO:0060070 canonical Wnt signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042995 cell projection
Protein Structure and Domains
PDB ID
InterPro IPR000539 Frizzled protein
IPR017981 GPCR, family 2-like
IPR020067 Frizzled domain
PFAM PF01534
PF01392
PRINTS PR00489
PIRSF
SMART SM00063
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A3KMX5
UniProt Splice Variant
Entrez Gene 515323
UniGene Bt.27485
RefSeq NP_001091502
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133364 DAAA02045003
GenPept AAI33365

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca