InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: FZD10

Summary

InnateDB Gene

IDBG-647861.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FZD10

Gene Name

frizzled-10 precursor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000007047

Encoded Proteins

IDBP-700648

frizzled-10

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111432:
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:47935477-47937432

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000009267

ENSBTAP00000009267

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0005515	protein binding
GO:0017147	Wnt-protein binding
GO:0030165	PDZ domain binding
GO:0042813	Wnt-activated receptor activity

Biological Process

GO:0001944	vasculature development
GO:0007166	cell surface receptor signaling pathway
GO:0007275	multicellular organismal development
GO:0007420	brain development
GO:0008406	gonad development
GO:0016055	Wnt signaling pathway
GO:0032855	positive regulation of Rac GTPase activity
GO:0032956	regulation of actin cytoskeleton organization
GO:0034259	negative regulation of Rho GTPase activity
GO:0038031	non-canonical Wnt signaling pathway via JNK cascade
GO:0043507	positive regulation of JUN kinase activity
GO:0060070	canonical Wnt signaling pathway