Version 5.4
Bos taurus Protein: RAG1
Summary
InnateDB Protein IDBP-700912.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAG1
Protein Name recombination activating gene 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000048319
InnateDB Gene IDBG-648145 (RAG1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016788 hydrolase activity, acting on ester bonds
GO:0016881 acid-amino acid ligase activity
GO:0042393 histone binding
GO:0042803 protein homodimerization activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0002250 adaptive immune response
GO:0002331 pre-B cell allelic exclusion
GO:0010390 histone monoubiquitination
GO:0016265 death
GO:0030183 B cell differentiation
GO:0033077 T cell differentiation in thymus
GO:0033151 V(D)J recombination
GO:0043029 T cell homeostasis
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045580 regulation of T cell differentiation
GO:0048538 thymus development
GO:0051865 protein autoubiquitination
GO:0070233 negative regulation of T cell apoptotic process
GO:0070244 negative regulation of thymocyte apoptotic process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001841 Zinc finger, RING-type
IPR019485 Zinc finger, V(D)J recombination-activating protein 1
PFAM PF13639
PF14634
PF10426
PRINTS
PIRSF
SMART SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MG60
UniProt Splice Variant
Entrez Gene 506302
UniGene
RefSeq XP_002693567
HUGO HGNC:9831
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02041329
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca