InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.79981

Summary

InnateDB Protein

IDBP-701542.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.79981

Protein Name

beta-1 adrenergic receptor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001639

InnateDB Gene

IDBG-648826 (BT.79981)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0004935	adrenergic receptor activity
GO:0004940	beta1-adrenergic receptor activity
GO:0005057	receptor signaling protein activity
GO:0005088	Ras guanyl-nucleotide exchange factor activity
GO:0005515	protein binding
GO:0030165	PDZ domain binding
GO:0031694	alpha-2A adrenergic receptor binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine
GO:0001997	positive regulation of the force of heart contraction by epinephrine-norepinephrine
GO:0002024	diet induced thermogenesis
GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0009409	response to cold
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0031649	heat generation
GO:0032320	positive regulation of Ras GTPase activity
GO:0040015	negative regulation of multicellular organism growth
GO:0042596	fear response
GO:0043950	positive regulation of cAMP-mediated signaling
GO:0045823	positive regulation of heart contraction
GO:0050873	brown fat cell differentiation
GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway

Cellular Component

GO:0005769	early endosome
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000507 Beta 1 adrenoceptor
IPR002232 5-Hydroxytryptamine 6 receptor
IPR002233 Adrenoceptor family
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
IPR019430 7TM GPCR, serpentine receptor class x (Srx)

PFAM

PF00001
PF10320
PF10328

PRINTS

PR00237
PR00561
PR01102
PR01103

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite