Version 5.4
Mus musculus Protein: Smarca2
Summary
InnateDB Protein IDBP-704486.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Smarca2
Protein Name
Synonyms 2610209L14Rik; brahma; brm; SNF2alpha; Snf2l2;
Species Mus musculus
Ensembl Protein ENSMUSP00000135116
InnateDB Gene IDBG-155600 (Smarca2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
They are also associated with 88 interaction(s) predicted by orthology.
Experimentally validated
Total 40 [view]
Protein-Protein 39 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 88 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001105 RNA polymerase II transcription coactivator activity
GO:0005515 protein binding
GO:0044212 transcription regulatory region DNA binding
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0008285 negative regulation of cell proliferation
GO:0030308 negative regulation of cell growth
GO:0035887 aortic smooth muscle cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0016514 SWI/SNF complex
GO:0045111 intermediate filament cytoskeleton
GO:0071778 WINAC complex
Protein Structure and Domains
PDB ID MGI:99603
InterPro IPR001487 Bromodomain
PFAM PF00439
PRINTS PR00503
PIRSF
SMART SM00297
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q99KH6
UniProt Splice Variant
Entrez Gene 67155
UniGene Mm.490734
RefSeq
MGI ID
MGI Symbol Smarca2
OMIM
CCDS
HPRD
IMGT
EMBL AC118249 AC118472 BC004653
GenPept AAH04653

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca