InnateDB Protein
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IDBP-711275.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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MOAP1
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Protein Name
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Synonyms
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AA987038; Map-1; Pnma4;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000137010
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InnateDB Gene
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IDBG-702743 (MOAP1)
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Protein Structure
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Function |
Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation (By similarity). {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Widely expressed, including in the brain. High expression levels in testis. {ECO:0000269PubMed:19366867}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
14 [view]
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Molecular Function |
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Biological Process |
GO:0006919
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activation of cysteine-type endopeptidase activity involved in apoptotic process
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GO:0030262
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apoptotic nuclear changes
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Cellular Component |
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PDB ID |
MGI:1915555
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9ERH6
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PhosphoSite |
PhosphoSite-Q9ERH6
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
64113
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UniGene |
Mm.489678
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RefSeq |
NP_001136409
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MGI ID |
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MGI Symbol |
Moap1
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OMIM |
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CCDS |
CCDS26122
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HPRD |
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IMGT |
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EMBL |
AF305551
AK019599
BC014715
BC055374
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GenPept |
AAG31787
AAH14715
AAH55374
BAB31810
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