InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pcsk4

Summary

InnateDB Protein

IDBP-711513.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pcsk4

Protein Name

Synonyms

AI647044; L21221; NEC 3; NEC3; PC4; SPC5;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000137809

InnateDB Gene

IDBG-173664 (Pcsk4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004252	serine-type endopeptidase activity

Biological Process

GO:0006508	proteolysis
GO:0007339	binding of sperm to zona pellucida
GO:0007340	acrosome reaction
GO:0009566	fertilization
GO:0048240	sperm capacitation

Cellular Component

GO:0002080

acrosomal membrane

Protein Structure and Domains

PDB ID

MGI:97514

InterPro

IPR000209 Peptidase S8/S53 domain
IPR009020 Proteinase inhibitor, propeptide
IPR015500 Peptidase S8, subtilisin-related

PFAM

PF00082

PRINTS

PR00723

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

M0QWG0

UniProt Splice Variant

Entrez Gene

18551

UniGene

Mm.299916

RefSeq

MGI ID

MGI Symbol

Pcsk4

OMIM

CCDS

HPRD

IMGT

EMBL

AC152062

GenPept