InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Prkar2b

Summary

InnateDB Protein

IDBP-713810.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Prkar2b

Protein Name

Synonyms

AI451071; AW061005; Pkarb2; PKARIIbeta; RII(beta);

Species

Mus musculus

Ensembl Protein

ENSMUSP00000135290

InnateDB Gene

IDBG-133755 (Prkar2b)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004862	cAMP-dependent protein kinase inhibitor activity
GO:0008603	cAMP-dependent protein kinase regulator activity
GO:0031625	ubiquitin protein ligase binding
GO:0034236	protein kinase A catalytic subunit binding

Biological Process

GO:0006631	fatty acid metabolic process
GO:0007612	learning
GO:2000480	negative regulation of cAMP-dependent protein kinase activity

Cellular Component

GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005886	plasma membrane
GO:0005952	cAMP-dependent protein kinase complex
GO:0097546	ciliary base

Protein Structure and Domains

PDB ID

MGI:97760

InterPro

IPR000595 Cyclic nucleotide-binding domain
IPR002373 cAMP/cGMP-dependent protein kinase
IPR018490 Cyclic nucleotide-binding-like

PFAM

PF00027

PRINTS

PR00103

PIRSF

SMART

SM00100

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

H3BK84

UniProt Splice Variant

Entrez Gene

19088

UniGene

Mm.490763

RefSeq

MGI ID

MGI Symbol

Prkar2b

OMIM

CCDS

HPRD

IMGT

EMBL

CT010463

GenPept