InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RBM39

Summary

InnateDB Protein

IDBP-71438.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RBM39

Protein Name

RNA binding motif protein 39

Synonyms

CAPER; CAPERalpha; FSAP59; HCC1; RNPC2;

Species

Homo sapiens

Ensembl Protein

ENSP00000253363

InnateDB Gene

IDBG-71434 (RBM39)

Protein Structure

UniProt Annotation

Function

Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process. {ECO:0000250}.

Subcellular Localization

Nucleus speckle. Note=Concentrated in nuclear speckles. Colocalizes with the core spliceosomal snRNP proteins.

Disease Associations

Tissue Specificity

Widely expressed. Highly expressed in pancreas, skeletal muscle, lung and brain. Expressed at intermediate level in kidney, liver and heart.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 152 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	152 [view]
Protein-Protein	147 [view]
Protein-DNA	5 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006396	RNA processing
GO:0006397	mRNA processing
GO:0008380	RNA splicing