Version 5.4
Mus musculus Protein: Gatad2a
Summary
InnateDB Protein IDBP-716066.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gatad2a
Protein Name
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000137386
InnateDB Gene IDBG-161054 (Gatad2a)
Protein Structure
UniProt Annotation
Function Transcriptional repressor (By similarity). Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2B (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus speckle {ECO:0000250}. Note=Speckled nuclear localization requires both CR1 and CR2 regions. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0030674 protein binding, bridging
GO:0046872 metal ion binding
Biological Process
GO:0001568 blood vessel development
GO:0001701 in utero embryonic development
GO:0001842 neural fold formation
GO:0006351 transcription, DNA-templated
GO:0010172 embryonic body morphogenesis
GO:0012501 programmed cell death
GO:0021506 anterior neuropore closure
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0016581 NuRD complex
GO:0016607 nuclear speck
Protein Structure and Domains
PDB ID MGI:2384585
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CHY6
PhosphoSite PhosphoSite-Q8CHY6
TrEMBL
UniProt Splice Variant
Entrez Gene 234366
UniGene Mm.394128
RefSeq NP_001106816
MGI ID
MGI Symbol Gatad2a
OMIM
CCDS CCDS52567
HPRD
IMGT
EMBL AK089074 BC019178 BC031407 BC038221
GenPept AAH19178 AAH31407 AAH38221 BAC40736

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca