Version 5.4
Homo sapiens Protein: NMRK1
Summary
InnateDB Protein IDBP-71627.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NMRK1
Protein Name chromosome 9 open reading frame 95
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000366004
InnateDB Gene IDBG-71621 (NMRK1)
Protein Structure
UniProt Annotation
Function Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the antitumor drugs tiazofurin and 3- deazaguanosine. {ECO:0000269PubMed:15137942}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0050262 ribosylnicotinamide kinase activity
Biological Process
GO:0009435 NAD biosynthetic process
GO:0016310 phosphorylation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000764 Uridine kinase like
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM
PRINTS PR00988
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NWW6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 54981
UniGene Hs.610743
RefSeq NP_001121075
HUGO HGNC:26057
OMIM 608704
CCDS CCDS47981
HPRD 09868
IMGT
EMBL AK000566 AL133548 AY611480 BC001366 BC036804 CH471089
GenPept AAH01366 AAH36804 AAT11928 BAA91259 CAH71570 CAH71571 EAW62568

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca