Homo sapiens Protein: DKFZP686D09174
Summary
InnateDB Protein IDBP-718027.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DKFZP686D09174
Protein Name
Synonyms HC3; MU; PMSA2; PSC2;
Species Homo sapiens
Ensembl Protein ENSP00000455744
InnateDB Gene IDBG-545594 (DKFZP686D09174)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004175 endopeptidase activity
GO:0004298 threonine-type endopeptidase activity
GO:0005515 protein binding
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000209 protein polyubiquitination
GO:0000278 mitotic cell cycle
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006521 regulation of cellular amino acid metabolic process
GO:0006915 apoptotic process
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0009615 response to virus
GO:0010467 gene expression
GO:0016032 viral process
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0044281 small molecule metabolic process
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051603 proteolysis involved in cellular protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0000932 cytoplasmic mRNA processing body
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005839 proteasome core complex
GO:0019773 proteasome core complex, alpha-subunit complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000426 Proteasome alpha-subunit, N-terminal domain
IPR001353 Proteasome, subunit alpha/beta
IPR029055 Nucleophile aminohydrolases, N-terminal
PFAM PF10584
PF00227
PRINTS
PIRSF
SMART SM00948
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6MZI6
UniProt Splice Variant
Entrez Gene 5683
UniGene
RefSeq
HUGO HGNC:9531
OMIM 176842
CCDS CCDS5467
HPRD 08907
IMGT
EMBL AC010132 AK290654 BC002900 BC047697 BX641097 CH236951 CH471073 CR450317 D00760
GenPept AAH02900 AAH47697 BAA00657 BAF83343 CAE46046 CAG29313 EAL24005 EAW94151 EAW94152 EAW94153