InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Igfbp4

Summary

InnateDB Protein

IDBP-718196.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Igfbp4

Protein Name

Synonyms

AI875747; Deb2; IGFBP-4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000135727

InnateDB Gene

IDBG-210907 (Igfbp4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005520	insulin-like growth factor binding

Biological Process

GO:0001558	regulation of cell growth
GO:0010906	regulation of glucose metabolic process
GO:0040008	regulation of growth
GO:0043410	positive regulation of MAPK cascade
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway
GO:0044342	type B pancreatic cell proliferation

Cellular Component

GO:0005615

extracellular space

Protein Structure and Domains

PDB ID

MGI:96439

InterPro

IPR000716 Thyroglobulin type-1
IPR022321 Insulin-like growth factor-binding protein family 1-6, chordata
IPR022327 Insulin-like growth factor-binding protein 4

PFAM

PF00086

PRINTS

PR01976
PR01980

PIRSF

SMART

SM00211

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

H3BLB7

UniProt Splice Variant

Entrez Gene

16010

UniGene

Mm.233799

RefSeq

MGI ID

MGI Symbol

Igfbp4

OMIM

CCDS

HPRD

IMGT

EMBL

AL591067 AL591366

GenPept