Version 5.4
Homo sapiens Protein: FEN1
Summary
InnateDB Protein IDBP-718591.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FEN1
Protein Name
Synonyms FEN-1; MF1; RAD2;
Species Homo sapiens
Ensembl Protein ENSP00000460402
InnateDB Gene IDBG-50439 (FEN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 58 [view]
Protein-Protein 54 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR006086 XPG-I domain
IPR008918 Helix-hairpin-helix motif, class 2
IPR020045 5\'-3\' exonuclease, C-terminal domain
PFAM PF00867
PF01367
PF09293
PRINTS
PIRSF
SMART SM00484
SM00279
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 2237
UniGene Hs.741166
RefSeq
HUGO HGNC:3650
OMIM 600393
CCDS
HPRD 02670
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca