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InnateDB Protein
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IDBP-719237.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Chn1
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Protein Name
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Synonyms
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0610007I19Rik; 0710001E19Rik; 1700112L09Rik; 2900046J01Rik; AI413815; ARHGAP2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000137106
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InnateDB Gene
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IDBG-180318 (Chn1)
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Protein Structure
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| Function |
GTPase-activating protein for p21-rac and a phorbol ester receptor. May play an important role in neuronal signal- transduction mechanisms (By similarity). Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance. {ECO:0000250, ECO:0000269PubMed:17785183}.
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
4
[view]
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| Protein-Protein |
4
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
5 [view]
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Molecular Function |
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| Biological Process |
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| Cellular Component |
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| PDB ID |
MGI:1915674
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| InterPro |
IPR000198
Rho GTPase-activating protein domain
IPR008936
Rho GTPase activation protein
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| PFAM |
PF00620
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| PRINTS |
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| PIRSF |
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| SMART |
SM00324
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q91V57
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| TrEMBL |
A7VK14
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| UniProt Splice Variant |
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| Entrez Gene |
108699
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| UniGene |
Mm.489675
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
Chn1
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| OMIM |
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| CCDS |
CCDS38145
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| HPRD |
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| IMGT |
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| EMBL |
AB264774
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| GenPept |
BAF80063
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Version 5.4