InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MACF1

Summary

InnateDB Protein

IDBP-721716.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MACF1

Protein Name

Synonyms

ABP620; ACF7; MACF; OFC4;

Species

Homo sapiens

Ensembl Protein

ENSP00000455823

InnateDB Gene

IDBG-96610 (MACF1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	43 [view]
Protein-Protein	43 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003779	actin binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0016887	ATPase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0007050	cell cycle arrest
GO:0016055	Wnt signaling pathway

Cellular Component

GO:0005856

cytoskeleton

Protein Structure and Domains

PDB ID

InterPro

IPR001101 Plectin repeat
IPR001715 Calponin homology domain
IPR002017 Spectrin repeat
IPR002048 EF-hand domain
IPR003108 Growth-arrest-specific protein 2 domain
IPR012337 Ribonuclease H-like domain
IPR018159 Spectrin/alpha-actinin
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain

PFAM