InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tnnt3

Summary

InnateDB Protein

IDBP-722630.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tnnt3

Protein Name

Synonyms

fTnT;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000136278

InnateDB Gene

IDBG-212580 (Tnnt3)

Protein Structure

UniProt Annotation

Function

Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed predominantly in skeletal muscle. {ECO:0000269PubMed:9249073}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005523	tropomyosin binding
GO:0030172	troponin C binding
GO:0030899	calcium-dependent ATPase activity
GO:0031013	troponin I binding
GO:0048306	calcium-dependent protein binding

Biological Process

GO:0003009	skeletal muscle contraction
GO:0006200	ATP catabolic process
GO:0006937	regulation of muscle contraction
GO:0006942	regulation of striated muscle contraction
GO:0043462	regulation of ATPase activity