InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RNMT

Summary

InnateDB Protein

IDBP-725970.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RNMT

Protein Name

Synonyms

hCMT1c; MET; RG7MT1;

Species

Homo sapiens

Ensembl Protein

ENSP00000466111

InnateDB Gene

IDBG-1256 (RNMT)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0004482	mRNA (guanine-N7-)-methyltransferase activity
GO:0005515	protein binding
GO:0008168	methyltransferase activity

Biological Process

GO:0006366	transcription from RNA polymerase II promoter
GO:0006370	7-methylguanosine mRNA capping
GO:0008152	metabolic process
GO:0010467	gene expression
GO:0016032	viral process
GO:0036265	RNA (guanine-N7)-methylation

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005845	mRNA cap binding complex
GO:0043235	receptor complex

Protein Structure and Domains

PDB ID

InterPro

IPR004971 mRNA (guanine-N(7))-methyltransferase domain
IPR013216 Methyltransferase type 11
IPR016899 mRNA (guanine-N(7))-methyltransferase
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF03291
PF08241

PRINTS

PIRSF

PIRSF028762

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O43148