InnateDB Protein
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IDBP-73680.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ATP5L
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Protein Name
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ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
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Synonyms
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ATP5JG;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000300688
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InnateDB Gene
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IDBG-73678 (ATP5L)
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Protein Structure
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Function |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
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Subcellular Localization |
Mitochondrion. Mitochondrion inner membrane.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
12
[view]
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Protein-Protein |
12
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
GO:0000276
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mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
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GO:0005739
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mitochondrion
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GO:0005743
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mitochondrial inner membrane
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GO:0005753
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mitochondrial proton-transporting ATP synthase complex
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GO:0070062
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extracellular vesicular exosome
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PDB ID |
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InterPro |
IPR006808
ATPase, F0 complex, subunit G, mitochondrial
IPR016702
Mitochondrial ATP synthase subunit g, animal
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PFAM |
PF04718
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PRINTS |
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PIRSF |
PIRSF017835
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O75964
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PhosphoSite |
PhosphoSite-O75964
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
10632
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UniGene |
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RefSeq |
NP_006467
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HUGO |
HGNC:14247
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OMIM |
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CCDS |
CCDS8397
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HPRD |
09815
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IMGT |
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EMBL |
AF070655
AF087846
AF092124
AK289568
AL050277
BC015128
BC070165
CH471065
CR533494
CR542211
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GenPept |
AAC61597
AAD20961
AAH15128
AAH70165
AAP97159
BAF82257
CAB43378
CAG38525
CAG47007
EAW67376
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