Version 5.4
Homo sapiens Protein: FN3KRP
Summary
InnateDB Protein IDBP-73749.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FN3KRP
Protein Name fructosamine 3 kinase related protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000269373
InnateDB Gene IDBG-73747 (FN3KRP)
Protein Structure
UniProt Annotation
Function Phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein- bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation. {ECO:0000269PubMed:14633848, ECO:0000269PubMed:15137908}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in erythrocytes. {ECO:0000269PubMed:15137908}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0008152 metabolic process
GO:0016310 phosphorylation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002575 Aminoglycoside phosphotransferase
IPR011009 Protein kinase-like domain
IPR016477 Fructosamine/Ketosamine-3-kinase
PFAM PF01636
PF03881
PRINTS
PIRSF PIRSF006221
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9HA64
PhosphoSite PhosphoSite-Q9HA64
TrEMBL I3L378
UniProt Splice Variant
Entrez Gene 79672
UniGene
RefSeq NP_078895
HUGO HGNC:25700
OMIM 611683
CCDS CCDS11817
HPRD 13546
IMGT
EMBL AC024361 AK022233 AL136631 AY360465 BC001458 BC007611 BC014408
GenPept AAH01458 AAH07611 AAH14408 AAQ72344 BAB13992 CAB66566

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca