InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Crtam

Summary

InnateDB Protein

IDBP-742583.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Crtam

Protein Name

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000137837

InnateDB Gene

IDBG-153804 (Crtam)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005515	protein binding

Biological Process

GO:0002355	detection of tumor cell
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0008037	cell recognition
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
GO:0050715	positive regulation of cytokine secretion
GO:0051606	detection of stimulus

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane

Protein Structure and Domains

PDB ID

MGI:1859822

InterPro

IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013162 CD80-like, immunoglobulin C2-set

PFAM

PF07679
PF07686
PF08205

PRINTS

PIRSF

SMART

SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite