InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Apobec3

Summary

InnateDB Protein

IDBP-743733.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Apobec3

Protein Name

Synonyms

Arp3; BC003314; Cem15; Rfv3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000135358

InnateDB Gene

IDBG-163088 (Apobec3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004126	cytidine deaminase activity
GO:0008270	zinc ion binding
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines

Biological Process

GO:0002244	hematopoietic progenitor cell differentiation
GO:0008152	metabolic process
GO:0009972	cytidine deamination
GO:0010529	negative regulation of transposition
GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:0051607	defense response to virus
GO:0070383	DNA cytosine deamination

Cellular Component

GO:0000932	cytoplasmic mRNA processing body
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

MGI:1933111

InterPro

IPR007904 APOBEC-like, C-terminal
IPR013158 APOBEC-like, N-terminal
IPR016193 Cytidine deaminase-like

PFAM

PF05240
PF08210

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3U5C5

UniProt Splice Variant

Entrez Gene

80287

UniGene

Mm.428054

RefSeq

MGI ID

MGI Symbol

Apobec3

OMIM

CCDS

HPRD

IMGT

EMBL

AB461449 AC113595 AK153719 AK167986 FJ602382

GenPept

ACP19551 BAE32154 BAE39977 BAH29961