InnateDB Protein
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IDBP-743822.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Polr2k
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Protein Name
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Synonyms
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ABC10-alpha; MafY; Mt1a; RPABC4; RPB10alpha; RPB12; RPB7.0;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000136975
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InnateDB Gene
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IDBG-134954 (Polr2k)
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Protein Structure
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Function |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively (By similarity). {ECO:0000250}.Factor that activates expression from a metal response element of the mouse metallothionein-I gene.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
14 [view]
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Molecular Function |
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Biological Process |
GO:0006351
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transcription, DNA-templated
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GO:0006360
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transcription from RNA polymerase I promoter
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GO:0006366
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transcription from RNA polymerase II promoter
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GO:0006383
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transcription from RNA polymerase III promoter
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Cellular Component |
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PDB ID |
MGI:102725
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InterPro |
IPR006591
RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4
IPR029040
RNA polymerase subunit RPABC4/transcription elongation factor Spt4
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PFAM |
PF03604
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PRINTS |
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PIRSF |
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SMART |
SM00659
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TIGRFAMs |
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Modification |
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SwissProt |
Q63871
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q545V5
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UniProt Splice Variant |
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Entrez Gene |
17749
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UniGene |
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RefSeq |
NP_075616
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MGI ID |
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MGI Symbol |
Polr2k
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OMIM |
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CCDS |
CCDS56980
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HPRD |
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IMGT |
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EMBL |
AK003023
BC028543
CH466570
S63758
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GenPept |
AAB27565
AAH28543
BAB22516
EDL29028
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