InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SNUPN

Summary

InnateDB Protein

IDBP-745421.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SNUPN

Protein Name

Synonyms

KPNBL; RNUT1; Snurportin1;

Species

Homo sapiens

Ensembl Protein

ENSP00000456224

InnateDB Gene

IDBG-23512 (SNUPN)

Protein Structure

UniProt Annotation

Function

Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. {ECO:0000269PubMed:9670026}.

Subcellular Localization

Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling protein. Its nuclear import involves the nucleocytoplasmic transport receptor importin beta. It is re- exported to the cytoplasm by the XPO1-dependent nuclear export receptor pathway.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.

Experimentally validated
Total	21 [view]
Protein-Protein	21 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000339	RNA cap binding
GO:0005515	protein binding
GO:0008565	protein transporter activity

Biological Process

GO:0000387	spliceosomal snRNP assembly
GO:0006606	protein import into nucleus
GO:0010467	gene expression
GO:0016070	RNA metabolic process
GO:0034660	ncRNA metabolic process
GO:0061015	snRNA import into nucleus