InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PKM2

Summary

InnateDB Protein

IDBP-745946.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PKM2

Protein Name

Synonyms

CTHBP; HEL-S-30; OIP3; PK3; PKM2; TCB; THBP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000457198

InnateDB Gene

IDBG-20117 (PKM2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 137 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	137 [view]
Protein-Protein	134 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0003824	catalytic activity
GO:0004743	pyruvate kinase activity
GO:0030955	potassium ion binding

Biological Process

GO:0006096	glycolytic process
GO:0016310	phosphorylation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR015793 Pyruvate kinase, barrel
IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain

PFAM

PF00224

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

H3BUW1

UniProt Splice Variant

Entrez Gene

5315

UniGene

Hs.737591

RefSeq

HUGO

HGNC:9021

OMIM

179050

CCDS

HPRD

01529

IMGT

EMBL

AC020779

GenPept