InnateDB Protein
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IDBP-746229.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SNUPN
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Protein Name
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Synonyms
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KPNBL; RNUT1; Snurportin1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000454852
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InnateDB Gene
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IDBG-23512 (SNUPN)
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Protein Structure
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Function |
Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. {ECO:0000269PubMed:9670026}.
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Subcellular Localization |
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling protein. Its nuclear import involves the nucleocytoplasmic transport receptor importin beta. It is re- exported to the cytoplasm by the XPO1-dependent nuclear export receptor pathway.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
21
[view]
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Protein-Protein |
21
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002652
Importin-alpha, importin-beta-binding domain
IPR017336
Snurportin-1
IPR024721
Snurportin-1, N-terminal
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PFAM |
PF01749
PF11538
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PRINTS |
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PIRSF |
PIRSF037955
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O95149
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PhosphoSite |
PhosphoSite-O95149
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TrEMBL |
H3BTA6
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UniProt Splice Variant |
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Entrez Gene |
10073
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UniGene |
Hs.21577
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RefSeq |
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HUGO |
HGNC:14245
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OMIM |
607902
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CCDS |
CCDS10281
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HPRD |
07441
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IMGT |
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EMBL |
AC105020
AC105036
AF039029
AK289475
BC004203
CH471136
CR456811
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GenPept |
AAC70906
AAH04203
BAF82164
CAG33092
EAW99245
EAW99246
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