InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HAUS2

Summary

InnateDB Protein

IDBP-746951.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HAUS2

Protein Name

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000456578

InnateDB Gene

IDBG-8013 (HAUS2)

Protein Structure

UniProt Annotation

Function

Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. {ECO:0000269PubMed:19369198, ECO:0000269PubMed:19427217}.

Subcellular Localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 72 experimentally validated interaction(s) in this database.

Experimentally validated
Total	72 [view]
Protein-Protein	72 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0000086	G2/M transition of mitotic cell cycle
GO:0000278	mitotic cell cycle
GO:0007067	mitotic nuclear division
GO:0051225	spindle assembly
GO:0051297	centrosome organization

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005813	centrosome
GO:0005819	spindle
GO:0005829	cytosol
GO:0005874	microtubule
GO:0070652	HAUS complex