Version 5.4
Homo sapiens Protein: TBL3
Summary
InnateDB Protein IDBP-747765.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBL3
Protein Name
Synonyms SAZD; UTP13;
Species Homo sapiens
Ensembl Protein ENSP00000454836
InnateDB Gene IDBG-9565 (TBL3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus, nucleolus {ECO:0000269PubMed:12429849}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005057 receptor signaling protein activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006364 rRNA processing
GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0032040 small-subunit processome
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR013934 Small-subunit processome, Utp13
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PF08625
PRINTS PR00320
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q12788
PhosphoSite PhosphoSite-Q12788
TrEMBL A0JLS5
UniProt Splice Variant
Entrez Gene 10607
UniGene Hs.707725
RefSeq NP_006444
HUGO HGNC:11587
OMIM 605915
CCDS CCDS10453
HPRD 09327
IMGT
EMBL AB209173 AC005363 AC005606 BC007620 BC010231 BC014007 BC035409 CH471112 U02609
GenPept AAA18945 AAH07620 AAH10231 AAH14007 AAH35409 BAD92410 EAW85589

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca