Version 5.4
Homo sapiens Protein: CTSL1
Summary
InnateDB Protein IDBP-74987.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTSL1
Protein Name cathepsin L1
Synonyms CATL; CTSL1; MEP;
Species Homo sapiens
Ensembl Protein ENSP00000340470
InnateDB Gene IDBG-74981 (CTSL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000668 Peptidase C1A, papain C-terminal
IPR013201 Proteinase inhibitor I29, cathepsin propeptide
PFAM PF00112
PF08246
PRINTS PR00705
PIRSF
SMART SM00645
SM00848
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8NG13
UniProt Splice Variant
Entrez Gene 1514
UniGene Hs.731507
RefSeq
HUGO HGNC:2537
OMIM 116880
CCDS
HPRD 00293
IMGT
EMBL AF304301 AF467444 AL160279
GenPept AAM89516 AAQ05021

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca