Version 5.4
Homo sapiens Protein: PHLPP2
Summary
InnateDB Protein IDBP-750148.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PHLPP2
Protein Name
Synonyms PHLPPL;
Species Homo sapiens
Ensembl Protein ENSP00000454519
InnateDB Gene IDBG-41059 (PHLPP2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0008152 metabolic process
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0045087 innate immune response
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048015 phosphatidylinositol-mediated signaling
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR001611 Leucine-rich repeat
IPR001932 Protein phosphatase 2C (PP2C)-like domain
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF00560
PF13504
PF13855
PF00481
PF07228
PRINTS
PIRSF
SMART SM00331
SM00332
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H3BMS5
UniProt Splice Variant
Entrez Gene 23035
UniGene Hs.709458
RefSeq
HUGO HGNC:29149
OMIM 611066
CCDS
HPRD 11118
IMGT
EMBL AB023148 AC009097 AK001854 AK124678 BC129927 BX647823
GenPept AAI29928 BAA76775 BAA91943 BAC85924

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca