Homo sapiens Protein: TBX6
Summary
InnateDB Protein IDBP-750857.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBX6
Protein Name
Synonyms SCDO5;
Species Homo sapiens
Ensembl Protein ENSP00000461223
InnateDB Gene IDBG-25611 (TBX6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001085 RNA polymerase II transcription factor binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0001191 RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0003700 sequence-specific DNA binding transcription factor activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007498 mesoderm development
GO:0009653 anatomical structure morphogenesis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001699 Transcription factor, T-box
IPR002070 Transcription factor, Brachyury
IPR008967 p53-like transcription factor, DNA-binding
PFAM PF00907
PRINTS PR00937
PR00938
PIRSF
SMART SM00425
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95947
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 6911
UniGene Hs.198301
RefSeq
HUGO HGNC:11605
OMIM 602427
CCDS
HPRD 03888
IMGT
EMBL AC012645 AC093512 AJ007989 AJ010279 AK022330 BC026031 CH471238
GenPept AAH26031 BAB14014 CAA07812 CAB37938 EAW79927