InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RHOT2

Summary

InnateDB Protein

IDBP-750874.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RHOT2

Protein Name

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000456855

InnateDB Gene

IDBG-7970 (RHOT2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.

Experimentally validated
Total	31 [view]
Protein-Protein	30 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0047497	mitochondrion transport along microtubule

Cellular Component

GO:0005622	intracellular
GO:0016020	membrane
GO:0031307	integral component of mitochondrial outer membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001806 Small GTPase superfamily
IPR003578 Small GTPase superfamily, Rho type
IPR003579 Small GTPase superfamily, Rab type
IPR013684 Mitochondrial Rho-like
IPR020849 Small GTPase superfamily, Ras type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00071
PF08477

PRINTS

PR00449

PIRSF

SMART

SM00174
SM00175
SM00173

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt