InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MMP15

Summary

InnateDB Protein

IDBP-751079.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MMP15

Protein Name

Synonyms

MT2-MMP; MTMMP2; SMCP-2;

Species

Homo sapiens

Ensembl Protein

ENSP00000457084

InnateDB Gene

IDBG-34054 (MMP15)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	1 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004222	metalloendopeptidase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006508

proteolysis

Cellular Component

GO:0031012

extracellular matrix

Protein Structure and Domains

PDB ID

InterPro

IPR001818 Peptidase M10, metallopeptidase
IPR012962 Peptidase M54, archaemetzincin
IPR021190 Peptidase M10A

PFAM

PF00413
PF07998

PRINTS

PR00138

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

4324

UniGene

Hs.80343

RefSeq

HUGO

HGNC:7161

OMIM

602261

CCDS

HPRD

03775

IMGT

EMBL

GenPept