InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KIF22

Summary

InnateDB Protein

IDBP-751161.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KIF22

Protein Name

Synonyms

A-328A3.2; KID; KNSL4; OBP; OBP-1; OBP-2; SEMDJL2;

Species

Homo sapiens

Ensembl Protein

ENSP00000454957

InnateDB Gene

IDBG-24634 (KIF22)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.

Experimentally validated
Total	17 [view]
Protein-Protein	12 [view]
Protein-DNA	5 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003777	microtubule motor activity
GO:0005524	ATP binding
GO:0008017	microtubule binding

Biological Process

GO:0006281	DNA repair
GO:0007018	microtubule-based movement
GO:0007067	mitotic nuclear division
GO:0007596	blood coagulation
GO:0008152	metabolic process
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II

Cellular Component

GO:0000776	kinetochore
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005871	kinesin complex
GO:0005874	microtubule
GO:0005925	focal adhesion

Protein Structure and Domains

PDB ID

InterPro

IPR001752 Kinesin, motor domain
IPR003583 Helix-hairpin-helix DNA-binding motif, class 1
IPR010994 RuvA domain 2-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00225

PRINTS

PR00380

PIRSF

SMART

SM00129
SM00278

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt