InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ANK3

Summary

InnateDB Protein

IDBP-75204.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ANK3

Protein Name

ankyrin 3, node of Ranvier (ankyrin G)

Synonyms

ANKYRIN-G; MRT37;

Species

Homo sapiens

Ensembl Protein

ENSP00000347436

InnateDB Gene

IDBG-75198 (ANK3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005200	structural constituent of cytoskeleton
GO:0005515	protein binding
GO:0008092	cytoskeletal protein binding
GO:0030507	spectrin binding
GO:0030674	protein binding, bridging
GO:0044325	ion channel binding
GO:0045296	cadherin binding

Biological Process

GO:0000281	mitotic cytokinesis
GO:0007009	plasma membrane organization
GO:0007016	cytoskeletal anchoring at plasma membrane
GO:0007165	signal transduction
GO:0007409	axonogenesis
GO:0010628	positive regulation of gene expression
GO:0010765	positive regulation of sodium ion transport
GO:0019228	neuronal action potential
GO:0043001	Golgi to plasma membrane protein transport
GO:0043266	regulation of potassium ion transport
GO:0045184	establishment of protein localization
GO:0045838	positive regulation of membrane potential
GO:0071709	membrane assembly
GO:0072659	protein localization to plasma membrane
GO:0072660	maintenance of protein location in plasma membrane
GO:0072661	protein targeting to plasma membrane
GO:1900827	positive regulation of membrane depolarization during cardiac muscle cell action potential
GO:2000651	positive regulation of sodium ion transmembrane transporter activity

Cellular Component

GO:0005764	lysosome
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0005923	tight junction
GO:0009925	basal plasma membrane
GO:0009986	cell surface
GO:0014704	intercalated disc
GO:0014731	spectrin-associated cytoskeleton
GO:0016323	basolateral plasma membrane
GO:0016328	lateral plasma membrane
GO:0030315	T-tubule
GO:0033268	node of Ranvier
GO:0042383	sarcolemma
GO:0043034	costamere
GO:0043194	axon initial segment
GO:0045211	postsynaptic membrane