Version 5.4
Homo sapiens Protein: DPEP2
Summary
InnateDB Protein IDBP-752411.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DPEP2
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000458977
InnateDB Gene IDBG-37912 (DPEP2)
Protein Structure
UniProt Annotation
Function Probable metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Lipid-anchor, GPI- anchor {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008235 metalloexopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008238 exopeptidase activity
GO:0008239 dipeptidyl-peptidase activity
GO:0016805 dipeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0006691 leukotriene metabolic process
GO:0019369 arachidonic acid metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005886 plasma membrane
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR008257 Renal dipeptidase family
PFAM PF01244
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H4A9
PhosphoSite PhosphoSite-Q9H4A9
TrEMBL I3L4H3
UniProt Splice Variant
Entrez Gene 64174
UniGene Hs.372633
RefSeq XP_005256147
HUGO HGNC:23028
OMIM 609925
CCDS CCDS10857
HPRD 07011
IMGT
EMBL AC040162 AJ295149 AK315090 AY358454 BC024021 CH471092
GenPept AAH24021 AAQ88819 BAG37555 CAC14667 EAW83200 EAW83202

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca