InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MYH11

Summary

InnateDB Protein

IDBP-753800.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYH11

Protein Name

Synonyms

AAT4; FAA4; SMHC; SMMHC;

Species

Homo sapiens

Ensembl Protein

ENSP00000458731

InnateDB Gene

IDBG-16251 (MYH11)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.

Experimentally validated
Total	24 [view]
Protein-Protein	24 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0005524	ATP binding
GO:0008307	structural constituent of muscle
GO:0051015	actin filament binding

Biological Process

GO:0006936	muscle contraction
GO:0006939	smooth muscle contraction
GO:0007411	axon guidance
GO:0008152	metabolic process
GO:0016192	vesicle-mediated transport
GO:0030241	skeletal muscle myosin thick filament assembly
GO:0048251	elastic fiber assembly
GO:0048739	cardiac muscle fiber development

Cellular Component

GO:0005829	cytosol
GO:0016020	membrane
GO:0016459	myosin complex
GO:0032982	myosin filament
GO:0042470	melanosome

Protein Structure and Domains

PDB ID

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR001609 Myosin head, motor domain
IPR002928 Myosin tail
IPR004009 Myosin, N-terminal, SH3-like
IPR009053 Prefoldin
IPR010989 t-SNARE
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00612
PF00063
PF01576
PF02736

PRINTS

PR00193

PIRSF

SMART

SM00015
SM00242

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt