Version 5.4
Homo sapiens Protein: PKNOX2
Summary
InnateDB Protein IDBP-75437.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PKNOX2
Protein Name PBX/knotted 1 homeobox 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000298282
InnateDB Gene IDBG-75435 (PKNOX2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00108, ECO:0000269PubMed:11549286}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003785 actin monomer binding
GO:0043565 sequence-specific DNA binding
GO:0051015 actin filament binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
GO:0015630 microtubule cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR008422 Homeobox KN domain
IPR009057 Homeodomain-like
PFAM PF00046
PF05920
PRINTS
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96KN3
PhosphoSite PhosphoSite-Q96KN3
TrEMBL H0YLX0
UniProt Splice Variant
Entrez Gene 63876
UniGene Hs.278564
RefSeq NP_071345
HUGO HGNC:16714
OMIM 613066
CCDS CCDS41730
HPRD 17857
IMGT
EMBL AB065001 AJ417081 AK298999 AK316268 AP000708 AP001007 AP003061 AP003069 BC045626 BX648615
GenPept AAH45626 BAB83665 BAH12921 BAH14639 CAD01142 CAH56146

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca