InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HOXD3

Summary

InnateDB Protein

IDBP-75768.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HOXD3

Protein Name

homeobox D3

Synonyms

Hox-4.1; HOX1D; HOX4; HOX4A;

Species

Homo sapiens

Ensembl Protein

ENSP00000249440

InnateDB Gene

IDBG-75766 (HOXD3)

Protein Structure

UniProt Annotation

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	7 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007160	cell-matrix adhesion
GO:0007219	Notch signaling pathway
GO:0009952	anterior/posterior pattern specification
GO:0010628	positive regulation of gene expression
GO:0030878	thyroid gland development
GO:0045666	positive regulation of neuron differentiation
GO:0048704	embryonic skeletal system morphogenesis
GO:0051216	cartilage development