Version 5.4
Homo sapiens Protein: HELZ
Summary
InnateDB Protein IDBP-757753.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HELZ
Protein Name
Synonyms DHRC; DRHC; HUMORF5;
Species Homo sapiens
Ensembl Protein ENSP00000463727
InnateDB Gene IDBG-65362 (HELZ)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000571 Zinc finger, CCCH-type
IPR014016 UvrD-like Helicase, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00642
PF00580
PRINTS
PIRSF
SMART SM00356
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P42694
PhosphoSite PhosphoSite-P42694
TrEMBL J3KT20
UniProt Splice Variant
Entrez Gene 9931
UniGene Hs.607072
RefSeq
HUGO HGNC:16878
OMIM 606699
CCDS
HPRD 10452
IMGT
EMBL AC005544 AC007448 BC094881 D29677
GenPept AAH94881 BAA06147

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca