InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HSD17B1

Summary

InnateDB Protein

IDBP-758059.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HSD17B1

Protein Name

Synonyms

EDH17B2; EDHB17; HSD17; SDR28C1;

Species

Homo sapiens

Ensembl Protein

ENSP00000466799

InnateDB Gene

IDBG-51038 (HSD17B1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004303	estradiol 17-beta-dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0047035	testosterone dehydrogenase (NAD+) activity

Biological Process

GO:0006694	steroid biosynthetic process
GO:0006703	estrogen biosynthetic process
GO:0008152	metabolic process
GO:0008202	steroid metabolic process
GO:0008210	estrogen metabolic process
GO:0044281	small molecule metabolic process
GO:0055114	oxidation-reduction process
GO:0060348	bone development
GO:0061370	testosterone biosynthetic process
GO:0071248	cellular response to metal ion

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0031965	nuclear membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002347 Glucose/ribitol dehydrogenase
IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
IPR011348 17beta-dehydrogenase
IPR013968 Polyketide synthase, KR

PFAM

PF00106
PF08659

PRINTS

PR00080
PR00081
PR01397

PIRSF

PIRSF000126
PIRSF000095

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt