Version 5.4
Homo sapiens Protein: CARD14
Summary
InnateDB Protein IDBP-759613.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CARD14
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000461806
InnateDB Gene IDBG-71483 (CARD14)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0050700 CARD domain binding
Biological Process
GO:0001934 positive regulation of protein phosphorylation
GO:0006915 apoptotic process
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0051092 positive regulation of NF-kappaB transcription factor activity
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR001315 CARD domain
IPR001478 PDZ domain
IPR011029 Death-like domain
PFAM PF00619
PF00595
PF13180
PRINTS
PIRSF
SMART SM00114
SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BXL6
PhosphoSite PhosphoSite-Q9BXL6
TrEMBL I3L4Q8
UniProt Splice Variant
Entrez Gene 79092
UniGene Hs.739340
RefSeq NP_001244899
HUGO HGNC:16446
OMIM 607211
CCDS CCDS58605
HPRD 06235
IMGT
EMBL AC087741 AF322642 AY032927 BC001326 BC018142 EU652409
GenPept AAG53403 AAH01326 AAH18142 AAK54453 ACF49506

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca