InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CCR7

Summary

InnateDB Protein

IDBP-759616.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CCR7

Protein Name

Synonyms

BLR2; CC-CKR-7; CCR-7; CD197; CDw197; CMKBR7; EBI1;

Species

Homo sapiens

Ensembl Protein

ENSP00000462631

InnateDB Gene

IDBG-47801 (CCR7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity

Biological Process

GO:0006954	inflammatory response
GO:0007186	G-protein coupled receptor signaling pathway
GO:0045087	innate immune response (InnateDB)
GO:0070098	chemokine-mediated signaling pathway

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000355 Chemokine receptor family
IPR001277 CXC chemokine receptor 4
IPR001718 CC chemokine receptor 7
IPR005383 CC chemokine receptor like 1
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS

PR00237
PR00657
PR00645
PR00641
PR01558

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite