InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: AP2S1

Summary

InnateDB Protein

IDBP-760013.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AP2S1

Protein Name

Synonyms

AP17; CLAPS2; FBH3; FBHOk; HHC3;

Species

Homo sapiens

Ensembl Protein

ENSP00000470898

InnateDB Gene

IDBG-59076 (AP2S1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	17 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0008565	protein transporter activity

Biological Process

GO:0006810	transport
GO:0006886	intracellular protein transport
GO:0006897	endocytosis
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0007268	synaptic transmission
GO:0007411	axon guidance
GO:0015031	protein transport
GO:0016032	viral process
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030100	regulation of endocytosis
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
GO:0048011	neurotrophin TRK receptor signaling pathway
GO:0048268	clathrin coat assembly
GO:0050690	regulation of defense response to virus by virus

Cellular Component

GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0030122	AP-2 adaptor complex
GO:0030666	endocytic vesicle membrane
GO:0030669	clathrin-coated endocytic vesicle membrane