Version 5.4
Homo sapiens Protein: SPHK1
Summary
InnateDB Protein IDBP-760096.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPHK1
Protein Name
Synonyms SPHK;
Species Homo sapiens
Ensembl Protein ENSP00000465002
InnateDB Gene IDBG-69650 (SPHK1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003951 NAD+ kinase activity
GO:0004143 diacylglycerol kinase activity
Biological Process
GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016310 phosphorylation
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001206 Diacylglycerol kinase, catalytic domain
PFAM PF00781
PRINTS
PIRSF
SMART SM00046
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL K7EJ32
UniProt Splice Variant
Entrez Gene 8877
UniGene Hs.739362
RefSeq
HUGO HGNC:11240
OMIM 603730
CCDS
HPRD 04768
IMGT
EMBL AC090699
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca