InnateDB Protein
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IDBP-760219.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CD300LF
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Protein Name
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000463743
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InnateDB Gene
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IDBG-67452 (CD300LF)
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Protein Structure
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Function |
Acts as an inhibitory receptor for myeloid cells and mast cells. Inhibits osteoclast formation. {ECO:0000269PubMed:15549731}.
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Subcellular Localization |
Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells. {ECO:0000269PubMed:15184070, ECO:0000269PubMed:15549731}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003599
Immunoglobulin subtype
IPR007110
Immunoglobulin-like domain
IPR013106
Immunoglobulin V-set domain
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PFAM |
PF07686
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PRINTS |
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PIRSF |
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SMART |
SM00409
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TIGRFAMs |
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Modification |
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SwissProt |
Q8TDQ1
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PhosphoSite |
PhosphoSite-Q8TDQ1
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
146722
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UniGene |
Hs.567706
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RefSeq |
NP_001276011
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HUGO |
HGNC:29883
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OMIM |
609807
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CCDS |
CCDS74148
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HPRD |
17635
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IMGT |
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EMBL |
AC016888
AC064805
AF251706
AF375480
AF375481
AK092757
AK315165
AY303545
AY358545
BC028199
DQ153249
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GenPept |
AAH28199
AAM19099
AAP42152
AAP42153
AAP57942
AAQ88909
AAZ81566
BAC03966
BAG37609
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