Version 5.4
Homo sapiens Protein: HNRNPH3
Summary
InnateDB Protein IDBP-76025.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HNRNPH3
Protein Name heterogeneous nuclear ribonucleoprotein H3 (2H9)
Synonyms 2H9; HNRPH3;
Species Homo sapiens
Ensembl Protein ENSP00000265866
InnateDB Gene IDBG-76023 (HNRNPH3)
Protein Structure
UniProt Annotation
Function Involved in the splicing process and participates in early heat shock-induced splicing arrest. Due to their great structural variations the different isoforms may possess different functions in the splicing reaction.
Subcellular Localization Nucleus {ECO:0000269PubMed:8999868}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 83 experimentally validated interaction(s) in this database.
Experimentally validated
Total 83 [view]
Protein-Protein 83 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006396 RNA processing
GO:0008380 RNA splicing
GO:0030855 epithelial cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
PFAM PF00076
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P31942
PhosphoSite PhosphoSite-P31942
TrEMBL A0A024QZP1
UniProt Splice Variant
Entrez Gene 3189
UniGene Hs.667283
RefSeq NP_036339
HUGO HGNC:5043
OMIM 602324
CCDS CCDS7278
HPRD 03818
IMGT
EMBL AF132360 AF132361 AF132362 AF132363 AF132364 AK091411 AK291547 AL117395 BC004511 BC039824 CH471083 L32610
GenPept AAD45179 AAF68843 AAF68844 AAF68845 AAF68846 AAF68847 AAF68848 AAF68849 AAF68850 AAF68851 AAF68852 AAH04511 AAH39824 BAF84236 BAG52353 CAB55897 EAW54280 EAW54281 EAW54282 EAW54284 EAW54285 EAW54287 EAW54288

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca