Version 5.4
Homo sapiens Protein: NUMBL
Summary
InnateDB Protein IDBP-760508.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUMBL
Protein Name
Synonyms CAG3A; CTG3a; NBL; NUMB-R; NUMBLIKE; NUMBR; TNRC23;
Species Homo sapiens
Ensembl Protein ENSP00000472400
InnateDB Gene IDBG-52025 (NUMBL)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 25 [view]
Protein-Protein 25 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007399 nervous system development
GO:0019221 cytokine-mediated signaling pathway
GO:0019538 protein metabolic process
GO:0021670 lateral ventricle development
GO:0021849 neuroblast division in subventricular zone
GO:0045087 innate immune response (InnateDB)
GO:0050769 positive regulation of neurogenesis
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR006020 PTB/PI domain
IPR010449 NUMB domain
IPR013625 Tensin phosphotyrosine-binding domain
IPR016698 Numb/numb-like
PFAM PF00640
PF14719
PF06311
PF08416
PRINTS
PIRSF PIRSF017607
SMART SM00462
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y6R0
PhosphoSite PhosphoSite-Q9Y6R0
TrEMBL M0R0Q4
UniProt Splice Variant
Entrez Gene 9253
UniGene Hs.326953
RefSeq
HUGO HGNC:8061
OMIM 604018
CCDS
HPRD 04931
IMGT
EMBL AC010412 AF015041 AK299484 BC001794 BT009807
GenPept AAD01549 AAP88809 BAH13046

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca