Version 5.4
Homo sapiens Protein: CAPNS1
Summary
InnateDB Protein IDBP-760647.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAPNS1
Protein Name
Synonyms 30K; CALPAIN4; CANP; CANPS; CAPN4; CDPS; CSS1;
Species Homo sapiens
Ensembl Protein ENSP00000464849
InnateDB Gene IDBG-46584 (CAPNS1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 64 experimentally validated interaction(s) in this database.
Experimentally validated
Total 64 [view]
Protein-Protein 63 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006508 proteolysis
GO:0008284 positive regulation of cell proliferation
GO:0022617 extracellular matrix disassembly
GO:0030198 extracellular matrix organization
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P04632
PhosphoSite PhosphoSite-P04632
TrEMBL U3KPR7
UniProt Splice Variant
Entrez Gene 826
UniGene Hs.515371
RefSeq XP_005259354
HUGO HGNC:1481
OMIM 114170
CCDS CCDS12489
HPRD 00240
IMGT
EMBL AC002984 AD001527 AK289606 AY789642 BC000592 BC007779 BC011903 BC017308 BC018931 BC021933 BC023643 BC064998 BT009775 M31502 M31503 M31504 M31505 M31506 M31507 M31508 M31509 M31510 M31511 X04106
GenPept AAA35646 AAB51183 AAB81546 AAH00592 AAH07779 AAH11903 AAH17308 AAH18931 AAH21933 AAH23643 AAH64998 AAP88777 AAV40829 BAF82295 CAA27726

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca