Version 5.4
Homo sapiens Protein: RBFOX3
Summary
InnateDB Protein IDBP-760787.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBFOX3
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000463653
InnateDB Gene IDBG-71149 (RBFOX3)
Protein Structure
UniProt Annotation
Function RNA-binding protein that regulates alternative splicing events. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0043484 regulation of RNA splicing
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043025 neuronal cell body
GO:0043204 perikaryon
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR017325 RNA binding protein Fox-1
IPR025670 Fox-1 C-terminal domain
PFAM PF00076
PF12414
PRINTS
PIRSF PIRSF037932
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6NFN3
PhosphoSite PhosphoSite-A6NFN3
TrEMBL
UniProt Splice Variant
Entrez Gene 146713
UniGene Hs.668802
RefSeq NP_001076044
HUGO HGNC:27097
OMIM
CCDS CCDS45805
HPRD 18730
IMGT
EMBL AC021534 AC073624 AK293617
GenPept BAG57077

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca